Low-Power Embedded Design Solutions and Low-Latency On-Chip Interconnect Architecture for System-On-Chip Design

This dissertation presents three design solutions to support several key system-on-chip (SoC) issues to achieve low-power and high performance. These are: 1) joint source and channel decoding (JSCD) schemes for low-power SoCs used in portable multimedia systems, 2) efficient on-chip interconnect architecture for massive multimedia data streaming on multiprocessor SoCs (MPSoCs), and 3) data processing architecture for low-power SoCs in distributed sensor network (DSS) systems and its implementation. The first part includes a low-power embedded low density parity check code (LDPC) - H.264 joint decoding architecture to lower the baseband energy consumption of a channel decoder using joint source decoding and dynamic voltage and frequency scaling (DVFS). A low-power multiple-input multiple-output (MIMO) and H.264 video joint detector/decoder design that minimizes energy for portable, wireless embedded systems is also designed. In the second part, a link-level quality of service (QoS) scheme using unequal error protection (UEP) for low-power network-on-chip (NoC) and low latency on-chip network designs for MPSoCs is proposed. This part contains WaveSync, a low-latency focused network-on-chip architecture for globally-asynchronous locally-synchronous (GALS) designs and a simultaneous dual-path routing (SDPR) scheme utilizing path diversity present in typical mesh topology network-on-chips. SDPR is akin to having a higher link width but without the significant hardware overhead associated with simple bus width scaling. The last part shows data processing unit designs for embedded SoCs. We propose a data processing and control logic design for a new radiation detection sensor system generating data at or above Peta-bits-per-second level. Implementation results show that the intended clock rate is achieved within the power target of less than 200mW. We also present a digital signal processing (DSP) accelerator supporting configurable MAC, FFT, FIR, and 3-D cross product operations for embedded SoCs. It consumes 12.35mW along with 0.167mm2 area at 333MHz

Baryonic Matter in the Hidden Local Symmetry Induced from Holographic QCD Models

Baryonic matter is studied in the Skyrme model by taking into account the roles of $\pi,$ $\rho$, and $\omega$ mesons through the hidden local symmetry up to $\mathcal{O}(p^4)$ terms including the homogeneous Wess-Zumino (hWZ) terms. Using the master formulas for the low energy constants derived from holographic QCD models the skyrmion matter properties can be quantitatively calculated with the input values of the pion decay constant $f_\pi$ and the vector meson mass $m_\rho^{}$. We find that the hWZ terms are responsible for the repulsive interactions of the $\omega$ meson. In addition, the self-consistently included $\mathcal{O}(p^4)$ terms with the hWZ terms is found to increase the half skyrmion phase transition point above the normal nucleon density.Comment: Contribution to SCGT12 "KMI-GCOE Workshop on Strong Coupling Gauge Theories in the LHC Perspective", 4-7 Dec. 2012, Nagoya Universit

Investigation of the SH3BP2 Gene Mutation in Cherubism

Cherubism is a rare developmental lesion of the jaw that is generally inherited as an autosomal dominant trait. Recent studies have revealed point mutations in the SH3BP2 gene in cherubism patients. In this study, we examined a 6-year-old Korean boy and his family. We found a Pro418Arg mutation in the SH3BP2 gene of the patient and his mother. A father and his 30-month-old younger brother had no mutations. Immunohistochemically, the multinucleated giant cells proved positive for CD68 and tartrate-resistant acid phosphatase (TRAP). Numerous spindle-shaped stromal cells expressed a ligand for receptor activator of nuclear factor kB (RANKL), but not in multinucleated giant cells. These results provide evidence that RANKL plays a critical role in the differentiation of osteoclast precursor cells to multinucleated giant cells in cherubism. Additionally, genetic analysis may be a useful method for differentiation of cherubism.</p

Anionic Depolymerization Transition in IrTe2

Selenium substitution drastically increases the transition temperature of iridium ditelluride (IrTe2) to a diamagnetic superstructure from 278 to 560 K. Transmission electron microscopy experiments revealed that this enhancement is accompanied by the evolution of nonsinusoidal structure modulations from q=1/5(101&amp;#772;) to q=1/6(101&amp;#772;) types. These comprehensive results are consistent with the concept of the destabilization of polymeric Te-Te bonds at the transition, the temperature of which is increased by chemical and hydrostatic pressure and by the substitution of Te with the more electronegative Se. This temperature-induced depolymerization transition in IrTe2 is unique in crystalline inorganic solids.open281

Interlocked chiral/polar domain walls and large optical rotation in Ni3TeO6

Chirality, i.e., handedness, pervades much of modern science from elementary particles, DNA-based biology to molecular chemistry; however, most of the chirality-relevant materials have been based on complex molecules. Here, we report inorganic single-crystalline Ni3TeO6, forming in a corundum-related R3 structure with both chirality and polarity. These chiral Ni3TeO6 single crystals exhibit a large optical specific rotation (alpha)-1355 degrees dm(-1) cm(3) g(-1). We demonstrate, for the first time, that in Ni3TeO6, chiral and polar domains form an intriguing domain pattern, resembling a radiation warning sign, which stems from interlocked chiral and polar domain walls through lowering of the wall energy. (C) 2015 Author(s)open0

Current Status of Biportal Endoscopic Decompression for Lumbar Foraminal Stenosis: Endoscopic Partial Facetectomy and Outcome Factors

Degenerative lumbar foraminal stenosis is relatively common condition in which the circumferential narrowing of the space available for the nerve root leads to back pain and radicular symptoms. The preferred surgical treatment to relieve the compression of the nerve root has not been established yet. Recently, several reports have shown good clinical outcomes in patients who underwent biportal endoscopic decompression for the treatment of degenerative lumbar foraminal stenosis. The floating-type biportal endoscopic technique could be used with various surgical instruments without docking in the narrowed foramen, unlike the full-endoscopic technique. Multiple sites can be accessed with more freedom in the approaching angle through triangulation and portal switching. We reviewed articles to understand putative outcome factors and discuss the appropriate indications for biportal endoscopic foraminal decompression. Lumbar lordosis, degenerative lumbar scoliosis, height of the posterior intervertebral disc and level of procedure were all related to clinical outcomes. The best indications and contraindications to the endoscopic foraminal decompression still depends on the surgeon’s skill level and evolving experience. However, we could suggest that biportal endoscopic spinal surgery is supposed to be an alternative treatment for foraminal decompression preserving motion and stability, and decreasing the need for fusion surgery in various lumbar degenerative disease

Early Dural Sac Termination with Lumbar Disc Herniation: A Mimic of Nerve Root Anomalies

The precise location of the dural sac (DS) end is necessary for preventing neural injury during spinal surgery or procedures. There has been no report on problems with spine surgery in patients with early DS termination. A 28-year-old woman presented with low back and leg pain involving the left S1 nerve root. Magnetic resonance imaging (MRI) revealed early DS termination at the lower one-third of the L5 vertebra and lumbar disc herniation at the L5/S1. Microscopic discectomy was performed instead of endoscopic discectomy to avoid unpredictable risks. Due to early DS termination, multiple nerve roots were identified, which look like nerve root congenital anomalies (Neidre and Macnab type II anomalies), and multiple separated nerve roots appeared to exit through a single foramen. After wide exposure by hemilaminectomy, which facilitated adequate visualization and mobilization of the involved nerve roots, the ruptured disc was identified and removed with gentle retraction, avoiding risk of excessive nerve root traction. Unlike other nerve root anomalies, early DS termination could be detected easily with preoperative MRI. Although this condition appears similar to other nerve root anomalies in the surgical field, it is possible to avoid inadvertent neural injury by closely investigating preoperative MRI. If early DS termination is suspected, it is necessary to consider a safer surgical approach

Anti-inflammatory activity of cinnamon water extract in vivo and in vitro LPS-induced models

BACKGROUND: Cinnamon bark is one of the most popular herbal ingredients in traditional oriental medicine and possesses diverse pharmacological activities including anti-bacterial, anti-viral, and anti-cancer properties. The goal of this study is to investigate the in vivo and in vitro inhibitory effect of cinnamon water extract (CWE) on lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α and its underlying intracellular mechanisms. METHODS: CWE was orally administrated to mice for 6 days prior to intraperitoneal injection of LPS. Serum levels of TNF-α and interleukin (IL)-6 were determined 1 hour after LPS stimulation. Peritoneal macrophages from thioglycollate-injected mice were isolated and assayed for viability, cytokine expression and signaling molecules upon LPS stimulation. CWE was further fractioned according to molecular size, and the levels of total polyphenols and biological activities of each fraction were measured. RESULTS: The oral administration of CWE to mice significantly decreased the serum levels of TNF-α and IL-6. CWE treatment in vitro decreased the mRNA expression of TNF-α. CWE blocked the LPS-induced degradation of IκBα as well as the activation of JNK, p38 and ERK1/2. Furthermore, size-based fractionation of CWE showed that the observed inhibitory effect of CWE in vitro occurred in the fraction containing the highest level of total polyphenols. CONCLUSIONS: Treatment with CWE decreased LPS-induced TNF-α in serum. In vitro inhibition of TNF-α gene by CWE may occur via the modulation of IκBα degradation and JNK, p38, and ERK1/2 activation. Our results also indicate that the observed anti-inflammatory action of CWE may originate from the presence of polyphenols

Hidden Local Symmetry and Infinite Tower of Vector Mesons for Baryons

In an effort to access dense baryonic matter relevant for compact stars in a unified framework that handles both single baryon and multibaryon systems on the same footing, we first address a holographic dual action for a single baryon focusing on the role of the infinite tower of vector mesons deconstructed from five dimensions. To leading order in 't Hooft coupling $\lambda=N_c g_{\rm YM}^2$, one has the Bogomol'nyi-Prasad-Sommerfield (BPS) Skyrmion that results when the warping of the bulk background and the Chern-Simons term in the Sakai-Sugimoto D4/D8-${\bar{\rm D8}}$ model are ignored. The infinite tower was found by Sutcliffe to induce flow to a conformal theory, i.e., the BPS. We compare this structure to that of the SS model consisting of a 5D Yang-Mills action in warped space and the Chern-Simons term in which higher vector mesons are integrated out while preserving hidden local symmetry and valid to $O(\lambda^0)$ and $O(p^4)$ in the chiral counting. We point out the surprisingly important role of the $\omega$ meson that figures in the Chern-Simons term that encodes chiral anomaly in the baryon structure and that may be closely tied to short-range repulsion in nuclear interactions.Comment: 9 pages, REVTeX, to be published in Phys. Rev.